Submitted by Amy Sercel MS RD CD
Edited by Marcia Bristow MS RDN CSSD CD
Have you ever had a
craving for something sweet but didn’t want the calories from a sugary
snack? Some people manage this by eating
foods made with artificial sweeteners.
Artificial sweeteners are ingredients that provide sweetness without
adding calories. Right now, there are
five FDA-approved artificial sweeteners: saccharin, acesulfame, aspartame,
neotame, and sucralose.1 They’re usually found in diet soda and
sugar-free versions of candy, ice cream, sports drinks, fruit spreads, and
juice.2
You might choose a food
made with artificial sweeteners to keep your overall calorie intake lower as
part of a goal to lose or maintain weight.
Unfortunately, studies have shown that using artificial sweeteners might
not really help with weight loss, and could also raise your risk for Type 2 Diabetes
and heart disease.2–4 Eating artificial sweeteners makes it more
difficult to regulate the amount of sugar-sweetened foods you eat later because
your brain no longer realizes that sugar-sweetened foods actually contain
calories.3 It also looks like artificial sweeteners don’t
satisfy the “reward center” of your brain the same way regular sugar does, so you’ll still crave sweets after eating an artificial sweetener and may be more
likely to overeat and gain weight as a result.2 Other studies also suggest that artificial
sweeteners change your microbiome, or the bacteria that live inside your
intestines. This change might
contribute to Type 2 Diabetes and weight gain.3
Some people react to the
controversy around artificial sweeteners by looking to a more natural,
calorie-free alternative sweetener: stevia.
Although it seems like stevia first showed up only a few years ago,
people have been using it as a sweetener for hundreds of years.5 The stevia found in food products is actually the
compound Rebaudioside A (Reb A), a highly purified extract from the plant Stevia rebaudiana. Reb A is the only part of the stevia plant
that has been generally recognized as safe by the Food and Drug Administration
(FDA). Stevia leaves, crude stevia
extracts, and whole leaf stevia have not been given FDA approval, and can
therefore only be sold as supplements.6,7
Although in the past stevia
was thought to be connected with fertility problems and birth defects, in 2008 the
FDA determined that Reb A is safe after reviewing studies submitted by the
companies that produce stevia. While the FDA reviewed these studies and decided
that they show Reb A’s safety, it’s difficult to solely rely upon studies that
were conducted by the company that makes a product; research without bias holds
more credibility. When a company who can
profit from a product funds a study about the safety of that product, the study
may be influenced by research or funding bias in which the results are either
consciously or unconsciously influenced to show the product in a more favorable
light.8,9
For this reason, when Reb A
received FDA approval in 2008 it was important for companies without ties to
stevia production to conduct more studies to truly prove stevia’s safety.6 Since then, not many studies have been performed
in humans and few of them are long-term.
However, some independent studies suggest that eating Reb A does not
result in any significant toxicity. A
systematic review by Massachusetts General Hospital found that stevia should be
evaluated farther for potential positive impacts on blood cholesterol levels
and insulin sensitivity.10 Other studies suggest that stevia doesn’t lead to
the same sugar cravings that other artificial sweeteners are known to cause.11–13 Since stevia has only been FDA-approved for 9
years, more research is needed to learn about stevia’s long-term health
impacts.
The amount of artificial
sweeteners and stevia that the FDA considers safe to eat in one day varies
depending on your body weight and the type of sweetener.14 For example, the FDA recommends eating no more
than 4 milligrams of stevia per kilogram of your body weight per day, but
states that it’s acceptable to eat up to 50 milligrams of aspartame per
kilogram of your body weight per day.15 Since more research is needed to learn about their
long-term health impacts, it is best to use them all in moderation. Limit the amount of artificial sweeteners and
stevia you use by choosing unprocessed foods, drinking water or milk instead of
diet soda or juice, and satisfying your cravings for sweet foods with fruit
instead of candy, desserts, or baked goods.
References:
1. Strawbridge H. Artificial sweeteners:
sugar-free, but at what cost? Harvard Health Blog.
http://www.health.harvard.edu/blog/artificial-sweeteners-sugar-free-but-at-what-cost-201207165030.
Published July 16, 2012. Accessed March 15, 2017.
2. Harvard T.H Chan
School of Public Health. Artificial Sweeteners. The Nutrition Source.
https://www.hsph.harvard.edu/nutritionsource/healthy-drinks/artificial-sweeteners/.
Published September 4, 2013. Accessed March 15, 2017.
3. Swithers SE.
Artificial sweeteners produce the counterintuitive effect of inducing metabolic
derangements. Trends Endocrinol Metab. 2013;24(9):431-441.
doi:10.1016/j.tem.2013.05.005.
4. Nettleton JE,
Reimer RA, Shearer J. Reshaping the gut microbiota: Impact of low calorie
sweeteners and the link to insulin resistance? Physiol Behav. 2016;164,
Part B:488-493. doi:10.1016/j.physbeh.2016.04.029.
5. Stevia: It’s Not
Just About Calories. ResearchGate.
https://www.researchgate.net/publication/228831065_Stevia_It’s_Not_Just_About_Calories.
Accessed March 21, 2017.
6. Is Stevia Safe? -
EatingWell. http://www.eatingwell.com/nutrition_health/nutrition_news_information/is_stevia_safe.
Accessed March 22, 2017.
7. Nutrition C for FS
and A. FDA Basics - What refined Stevia preparations have been evaluated by FDA
to be used as a sweetener? https://www.fda.gov/AboutFDA/Transparency/Basics/ucm214865.htm.
Accessed March 22, 2017.
8. Six
industry-funded studies. The score for the year: 156/12. Food Polit Marion
Nestle. March 2016.
http://www.foodpolitics.com/2016/03/six-industry-funded-studies-the-score-for-the-year-15612/.
Accessed April 22, 2017.
9. Who pays for
science? http://undsci.berkeley.edu/article/who_pays. Accessed April 22, 2017.
10. Ulbricht C, Isaac
R, Milkin T, et al. An evidence-based systematic review of stevia by the
Natural Standard Research Collaboration. Cardiovasc Hematol Agents Med Chem.
2010;8(2):113-127.
11. Anton SD, Martin
CK, Han H, et al. Effects of stevia, aspartame, and sucrose on food intake,
satiety, and postprandial glucose and insulin levels. Appetite. 2010;55(1):37-43.
doi:10.1016/j.appet.2010.03.009.
12. Abo Elnaga NIE,
Massoud MI, Yousef MI, Mohamed HHA. Effect of stevia sweetener consumption as
non-caloric sweetening on body weight gain and biochemical’s parameters in
overweight female rats. Ann Agric Sci. 2016;61(1):155-163.
doi:10.1016/j.aoas.2015.11.008.
13. Shivanna N, Naika
M, Khanum F, Kaul VK. Antioxidant, anti-diabetic and renal protective
properties of Stevia rebaudiana. J Diabetes Complications.
2013;27(2):103-113. doi:10.1016/j.jdiacomp.2012.10.001.
14. Artificial
Sweetener Labeling Initiative. The Sugar Association.
https://www.sugar.org/nutritional-advocacy/artificial-sweetener-labeling-initiative/.
Accessed March 15, 2017.
15. Nutrition C for FS
and A. Food Additives & Ingredients - Additional Information about
High-Intensity Sweeteners Permitted for use in Food in the United States.
https://www.fda.gov/food/ingredientspackaginglabeling/foodadditivesingredients/ucm397725.htm#Steviol_glycosides.
Accessed April 22, 2017.